Damaged Tissue & Organ Transplants

Liver Cirrhosis

Cirrhosis is a condition where scarring damages the liver. This can block the blood flow through the liver, affecting its function. Because the liver participates in many different functions in the body like digestion, blood clotting, breaking down alcohol and drugs, and storage of vitamins and minerals, cirrhosis may lead to serious health complications.

Regenerative properties of mesenchymal stem cells are being explored for treating liver cirrhosis. They have been used to regenerate scarred liver tissue in mice.

TRIAL HYPOTHESIS CLINICAL TRIAL ID
Can patients with liver cirrhosis be safely and effectively treated via intravenous administration of umbilical mesenchymal stem cells? NCT01573923 Alliancells Bioscience Corporation Limited, China
Using umbilical cord mesenchymal stem cells transplants to treat patients with damaged livers due to cirrhosis NCT01342250 Shenzhen Beike Bio-Technology Co., Ltd, China
Multicenter study looking at the safety and effectiveness of using umbilical cord mesenchymal stem cell transfusions to treat liver cirrhosis. NCT03529136 Jinan Hospital for Infectious Diseases
Is infusing umbilical cord mesenchymal stem cells through the hepatic artery an effective method for treating liver cirrhosis? NCT01224327 Qingdao University
Evaluating the safety and effectiveness of administering umbilical cord mesenchymal stem cells via the hepatic artery to treat patients with hepatitis B-related liver cirrhosis. NCT01728727 Fourth Military Medical University, China
Looking at using mesenchymal stem cells (derived from bone marrow and umbilical cord tissue) to treat liver cirrhosis. NCT01877759 Chaitanya Hospital, Pune, India
Can umbilical mesenchymal stem cells improve the outcome of liver transplants? NCT01690247 Beijing 302 Hospital, China
Using the umbilical cord stem cells (19#iSCLife®-LC) to treat liver cirrhosis caused by hepatitis B. NCT03826433 Xiangya Hospital Central South University, China